Stiff neck. Aching hips. Weak ankles. Creaking knees. Immobile hands. Joint pain Most of us experience it. Athletes and bodybuilders believe it’s a”necessary evil” in their training. And as we approach our senior years, we now accept it as part of growing old.

However, joint pain isn’t always brought on by strains, sprains, aging or injuries. It may also be attributed to ailments like arthritis, bursitis, and arthritis.

The great news is that you do not have to suffer it. Relief is available in many different ways and forms, ranging from physical therapy and nutritional supplements to drugs and joint replacement.

While we’re not professional medical professionals, we plan to help you alleviate your joint pain. And the very best way we could do that is to vet joint supplements.

So, we conducted an extensive study on the greatest joint pain relief supplements on the market today. We hope this helps you make an educated choice on managing your problem.

How Can Joint Pain Relief Supplements Work?

The best joint supplements contain at least 2 of the following components:

Glucosamine Sulfate. This substance occurs naturally in the cartilage of your joint, keeping it healthy and lubricated.

In supplements, it is harvested from the shells of crustaceans (shrimps, crabs, lobsters) and shellfish.

Chondroitin sulfate. Your body naturally creates this ingredient to prevent the breakdown of cartilage. It also reduces joint inflammation and pain.

Manufacturers of supplements source this material from cow trachea or pork byproducts.

Calcium. Almost all of your bodily functions — from the pumping of your heart into the regeneration of your muscles use calcium. Consequently, when you are calcium deficient, then your body uses what is in your bones.

Vitamin D3. When sunlight hits your skin, your body generates Vitamin D3, one of the critical types of vitamin D. Its main role is to assist your bones to absorb calcium.

Other ingredients that are important:

  • MSM (Methylsulfonylmethane)
  • Turmeric
  • Omega-3
  • SAMe (S-adenosyl-L-methionine)
  • Bromelain
  • Stinging Nettle Root Extract
  • Devil’s Claw

Some of these can cause unwanted effects. Consequently, it’s ideal to consult your doctor to determine if a joint pain relief supplement is safe for you to utilize.

Why Require Joint Supplements?

Joint pain is a critical problem which affects almost all aspects of your life. It may affect your performance on the job and manifest in your interactions with different people.

Why should you live with this condition as soon as you’re able to get rid of it? You have various options depending on your lifestyle and tastes.

We highly recommend regular exercise combined with joint supplements. These are more affordable, more convenient and safer alternatives to drugs and joint replacement surgery.

How to Pick the Ideal Joint Pain Relief Supplements

Because joint pain is a symptom of many different conditions, you need to secure a proper diagnosis from your physician. This will ensure you have the right treatment and choose the ideal supplement.

Not many joint pain relief supplements are created exactly the same; each contains a unique combination of components. Being aware of what’s causing your pain can allow you to pick the best nutritional supplement for your needs.

Your doctor has the knowledge and instruments to determine the underlying cause of your joint pain.

While there are plenty of joint pain relief goods available on the market today, we’ve narrowed down the list of the finest joint pain relief nutritional supplements that you can choose from. Have a look at our best-reviewed joint supplements below.

1. Joint Advance

Top on our list of finest joint supplements is Joint Advance out of Pacific Naturals, a trusted name in beauty and health products.

The manufacturer promises that its unique formulation offers relief from joint pain, improvement in mobility, and increased joint lubrication.

It comprises only plant-derived ingredients which are scientifically proven to work in supporting joint health.

joint advance reviews


  • wide selection of natural ingredients, all for joint pain relief
  • vegetarian and vegan-friendly
  • clinical trials support every ingredient
  • comes with a combined protection diet manual
  • 90-day Money-back Guarantee
  • life membership accessibility to company’s online fitness program


  • available only online

Three things impressed us concerning Joint Advance, which got our best vote on this listing.

To start with, your purchase comes with a joint protection diet guide. Most of you might feel that joint pain is caused exclusively by physical strain, trauma, aging or certain illnesses.

Nonetheless, this isn’t so. There are real food and beverages that trigger acids in your body, leading to joint problems. Some of them could worsen present joint issues.

This can be a valuable support in your fight against joint pain.

Second, your very first purchase automatically provides you access to the company’s online exercise program. This includes, amongst others, exercise regimens for different kinds of joint pain.

And third, you have 90 days to learn whether this joint supplement is ideal for you. If it is not, it is possible to return the product and receive your money back.

A word of warning: Though the organic ingredients in Joint Advance have no known side effects, it contains ginger, which may lead to mild discomforts if you are pregnant or nursing.

2. Flexoplex

The business is known for using formulations produced under the supervision of medical and nutritional professionals.

This product generally supports your overall joint health. Specifically, it targets your joint mobility by strengthening, preserving and improving its inherent characteristics.

It also numbs the pain sensors inside your physique. As a result, you will feel rapid relief from joint pain.



  • all natural ingredients at optimal levels
  • compounds are pharmacy-grade
  • comprehensive website
  • facilities are approved by the FDA
  • offers a starter bottle in a lesser price
  • 60-day money back guarantee


  • may cause a headache
  • reviewers stated it’s less potent compared to other joint supplements

It prevents inflammation and decreases swelling and pain due to arthritis.

But what we like best about this nutritional supplement is the healing procedure that your joints will encounter when you take it.

The very first step is that the repair of the damages on your joints. Afterward, your joint cartilage is going to be rebuilt. And lastly, your joints will receive sufficient lubrication so you can enjoy increased freedom.

All these steps are essential to your joint inflammation to subside. And no inflammation means no pain.

We just wish that the maker of Flexoplex conducted clinical tests to prove the effectiveness of the product. This way, the side effects we mentioned above could probably have been prevented.

And to quote one of their customers: Povidone, shellac, soy lecithin and silicon dioxide don’t have any health functions within this supplement. We concur.

3. Doctor’s Best Glucosamine Chondroitin MSM

By Doctor’s Best Inc. comes our third option for today’s best joint supplements: Doctor’s Best Glucosamine Chondroitin MSM. The company manufactures a range of nutritional supplements. They enjoy the fact that their formulations are science-based and tested for quality.

Most notable about this item is that it contains MSM, which not all joint supplements have. This sulfur chemical is produced not only by the human body but also by animals, fruits, vegetables, and grains.

It reduces joint pain and inflammation throughout the sulfur your body uses to form connective tissues. Additionally, it calms neural impulses which send messages of pain to your mind.

Doctor’s Best Glucosamine Chondroitin MSM


  • unites the best 3 joint pain relief ingredients
  • may be obtained with or without food
  • gluten-free, soy-free and non-GMO
  • handed Quality Assurance testing
  • available online and at physical retail stores


  • may cause stomach cramps and bloat
  • its glucosamine is sourced from crustaceans and shellfish, which can cause allergic reactions
  • dosage is 4 capsules every day
  • the return policy is difficult and expensive

Doctors wholeheartedly concur that glucosamine, chondroitin, and MSM are one of the very best components for joint health administration. The finest joint pain relief supplements include these in their own formulations.

Doctor’s Best Glucosamine Chondroitin MSM employs scientific processes to make certain you get these ingredients in the maximum quality.

Using potassium chloride, they purify, sulfate and stabilize glucosamine to eliminate impurities.

In addition, sophisticated laboratory analytical methods guarantee at least 90 percent purity of the chondroitin inside this supplement.

In addition, the MSM ingredient undergoes a four-stage process that removes pollutants and impurities from it.

However, this product isn’t right for everybody. If you are taking drugs for diabetes, glaucoma or warfarin, it might interact with your medication.

And as mentioned above, the crustacean and shellfish derived glucosamine isn’t safe for people sensitive to it. Additionally, this makes the product a no-no for vegetarians and vegans.

4. Instaflex

Number four on our list of best joint pain relief supplements is Instaflex, formulated under the guidance of Dr. David Katz.

Dr. Katz is the Director and also Co-Founder of the Yale Prevention Research Center.

The manufacturer of the product followed Dr. Katz’ information to use natural ingredients that target joint pain in the source. Furthermore, he instructed them to steer clear of substances which only mask the pain.

instaflex reviews


  • endorsed by professional football player Doug Flutie
  • merchandise was subject to clinical tests
  • many favorable customer reviews
  • 30-day money back guarantee
  • 2-week free trial interval


  • may Lead to skin lumps, cramps, sluggishness, itchiness and upset stomach
  • unexpected side effects were due to lack of information about ingredients 
  • expensive
  • trial interval involves registration in the Organization’s auto shipping plan

Plus it utilizes ingredients encouraged by clinical research and scientific proof.

One of these is turmeric, which can be successful in relieving joint pain, even though not widely used in other joint pain relief supplements.

Traditional Chinese and Indian medication use this plant to treat the symptoms of arthritis: joint pain, inflammation, and stiffness.

On the flip side, Western clinical studies show that it’s better in the prevention, rather than decrease, of arthritis joint inflammation.

However, Instaflex is missing glucosamine and chondroitin, which doctors say would be the top two components in combating joint pain.

Accordingly, despite all the scientific evidence supporting its efficacy, this item is most likely not as successful as the other greatest joint pain relief supplements which contain those two ingredients.

5. Arthro 7

Our fifth choice of the best joint supplements is U.S. Physicians’ Clinical’s Arthro 7. The company guarantees the product works within 14 days.

This supplement has been around for at least two decades, and eight million components of this have been sold at that moment.

On the manufacturer’s site, you will find a chart demonstrating the results of a clinical evaluation they conducted to prove the supplement’s efficacy.

Arthro 7 reviews


  • FDA approved manufacturing facility
  • a clinical study published in the Nutrition and Dietary Supplements and in peer-reviewed journals
  • fermented, shellfish-free, non-GMO
  • the website includes detailed product info
  • 60-day Money-back Guarantee


  • presented research is endorsed by only one doctor
  • not so great customer service
  • not vegetarian or vegan-friendly
  • costly

Arthro 7 made it to this listing of best joint pain relief supplements chiefly because of its remaining power. It started out as one of only a couple joint supplements supplying joint pain relief.

Twenty years after, the item continues to flourish in a marketplace that has lots of new players, each offering unique properties.

We wonder why the manufacturer risks including ingredients that alienate prospective users.

One of these is collagen, which can be sourced from creatures. Back in Arthro 7, it comes from a chicken. This makes the supplement unsafe for people allergic to poultry. Not to mention vegetarians and vegans, who probably won’t touch it only because of the one ingredient.

It can also decrease your desire.

This enzyme naturally happens in your body to help with digestion and processing of fat.

But some studies suggest that nursing or pregnant women do not react well to this particular substance. And in case you’ve got cystic fibrosis, it’s dangerous for you also.

Side effects from taking Lipase 30 include nausea, cramping, and nausea.


Joint pain is more prevalent than you think, though it comes in different forms due to different causes. Some are light, yet others might be painful. Some last a few weeks, others continue for months.

Whatever it is for you, be certain it can be managed, sometimes even removed. Your joints will work better when you eliminate inflammation.

Taking one of the best joint supplements we recommend is 1 way of accomplishing this. And it is a great way.

There are just a couple of aspects to think about when deciding on the right product for you.

First of all, examine the components. Read labels to make sure there’s nothing you are sensitive to. It is especially important when you are on medication for a critical condition.

Also, be aware that the most effective components, glucosamine, and chondroitin, are slow-acting. If your pain becomes unbearable, pick a nutritional supplement with extra, fast-acting substances.

If you have a genetic predisposition to developing joint cartilage problems, your nutritional supplement has to be safe to endure for a long period.

The same goes for you if you are an athlete. Your workout regimen and sports activities make you more prone to developing knee and hip arthritis.

The final element is to keep in mind that the best joint pain relief nutritional supplements will not completely solve your joint pain. Rather, you must also create some lifestyle changes:

  • Lose weight.
  • Exercise regularly under the guidance of a physical therapist.
  • Wear correct footwear that offers cushion.
  • Avoid processed foods with omega-6 fatty acids and carbs with high glycemic index.

Last, keep in mind that when it comes to joint pain, physicians are your very best buddy. Long-lasting relief from such supplements is possible when you follow your physician’s advice.

Top 5 Joint Pain Relief Supplements In 2018
Times Nutrition is the most trusted health organization to provide information and Supplement Review after research. Don't buy any product until you read reviews.


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